Publications
Click HERE for an updated list of publications.
Selected Key Publications
Haq R, Fisher DE (2011). Biology and clinical relevance of the micropthalmia family of transcription factors in human cancer. Journal of Clinical Oncology, 29(25):3474-82.
Yokoyama S*, Woods SL*, Boyle G*, Aoude LG*, MacGregor S*, Zismann V*, Gartside M, Cust AE, Haq R, et al. (2011). A novel recurrent mutation in MITF predisposes to familial and sporadic melanoma. Nature, Nov 13;480(7375):99-103.
Shoag J, Haq R, Zhang M, Liu L, Rowe GC, Jiang A, Koulisis N, Farrel C, Amos CI, Wei Q, Lee JE, Zhang J, Kupper TS, Qureshi AA, Cui R, Han J, Fisher DE, Arany Z (2013). PGC-1 coactivators regulate MITF and the tanning response. Molecular Cell, 49(1):145-57.
Haq R, Yokoyama S, Hawryluk EB, Jönsson GB, Frederick DT, McHenry K, Porter D, Tran TN, Love KT, Langer R, Anderson DG, Garraway LA, Duncan LM, Morton DL, Hoon DS, Wargo JA, Song JS, Fisher DE (2013). BCL2A1 is a lineage-specific antiapoptotic melanoma oncogene that confers resistance to BRAF inhibition. Proc Natl Acad Sci U S A, 110(11):4321-6.
Haq R, Shoag S, Andreu-Perez P, Yokoyama S, Edelman H, Hurley AD, Nellore A, Wargo JA, Song JS, Fisher DE*, Arany Z*, Widlund HR* (2013). Oncogenic BRAF regulates oxidative metabolism via PGC1α and MITF. Cancer Cell, Mar 18;23(3):302-15. [Previewed in Cancer Cell, Cancer Discovery, Nature Reviews Cancer, and Pigment Cell & Melanoma Research].
Haq R (2014). Metabolic dysregulation in melanoma: Cause or consequence? Cancer Discovery, 4(4):390-1.
Montero J, Gstalder C, Kim DJ, Sadowicz D, Miles W, Manos M, Cidado JR, Secrist JR, Tron AE, Flaherty K, Hodi FS, Yoon CH, Letai A, Fisher DE, Haq R (2019). Destabilization of NOXA mRNA as a common resistance mechanism to targeted therapies. Nat Communications, Nov 14;10(1):5157. PMCID: PMC 31727958.
Gstalder C, Liu D, Miao D, Lutterbach B, DeVine AL, Lin C, Shettigar M, Pancholi P, Buchbinder EI, Carter SL, Manos MP, Rojas-Rudilla V, Brennick R, Gjini E, Chen PH, Lako A, Rodig S, Yoon CH, Freeman GJ, Barbie DA, Hodi FS, Miles W, Van Allen EM, Haq R.
Cancer Discov. 2020 May 5. pii: CD-19-1416. doi: 10.1158/2159-8290.CD-19-1416.
Selected Key Publications
Haq R, Fisher DE (2011). Biology and clinical relevance of the micropthalmia family of transcription factors in human cancer. Journal of Clinical Oncology, 29(25):3474-82.
Yokoyama S*, Woods SL*, Boyle G*, Aoude LG*, MacGregor S*, Zismann V*, Gartside M, Cust AE, Haq R, et al. (2011). A novel recurrent mutation in MITF predisposes to familial and sporadic melanoma. Nature, Nov 13;480(7375):99-103.
Shoag J, Haq R, Zhang M, Liu L, Rowe GC, Jiang A, Koulisis N, Farrel C, Amos CI, Wei Q, Lee JE, Zhang J, Kupper TS, Qureshi AA, Cui R, Han J, Fisher DE, Arany Z (2013). PGC-1 coactivators regulate MITF and the tanning response. Molecular Cell, 49(1):145-57.
Haq R, Yokoyama S, Hawryluk EB, Jönsson GB, Frederick DT, McHenry K, Porter D, Tran TN, Love KT, Langer R, Anderson DG, Garraway LA, Duncan LM, Morton DL, Hoon DS, Wargo JA, Song JS, Fisher DE (2013). BCL2A1 is a lineage-specific antiapoptotic melanoma oncogene that confers resistance to BRAF inhibition. Proc Natl Acad Sci U S A, 110(11):4321-6.
Haq R, Shoag S, Andreu-Perez P, Yokoyama S, Edelman H, Hurley AD, Nellore A, Wargo JA, Song JS, Fisher DE*, Arany Z*, Widlund HR* (2013). Oncogenic BRAF regulates oxidative metabolism via PGC1α and MITF. Cancer Cell, Mar 18;23(3):302-15. [Previewed in Cancer Cell, Cancer Discovery, Nature Reviews Cancer, and Pigment Cell & Melanoma Research].
Haq R (2014). Metabolic dysregulation in melanoma: Cause or consequence? Cancer Discovery, 4(4):390-1.
Montero J, Gstalder C, Kim DJ, Sadowicz D, Miles W, Manos M, Cidado JR, Secrist JR, Tron AE, Flaherty K, Hodi FS, Yoon CH, Letai A, Fisher DE, Haq R (2019). Destabilization of NOXA mRNA as a common resistance mechanism to targeted therapies. Nat Communications, Nov 14;10(1):5157. PMCID: PMC 31727958.
Gstalder C, Liu D, Miao D, Lutterbach B, DeVine AL, Lin C, Shettigar M, Pancholi P, Buchbinder EI, Carter SL, Manos MP, Rojas-Rudilla V, Brennick R, Gjini E, Chen PH, Lako A, Rodig S, Yoon CH, Freeman GJ, Barbie DA, Hodi FS, Miles W, Van Allen EM, Haq R.
Cancer Discov. 2020 May 5. pii: CD-19-1416. doi: 10.1158/2159-8290.CD-19-1416.